Rhesus IL17BR / IL17RB / IL-17 Receptor B Protein (Fc Tag)

IL17BR, IL17RB, IL-17 Receptor B

Catalog Number	P90140-C02H
Organism Species	Rhesus
Host	Human Cells
Synonyms	IL17BR, IL17RB, IL-17 Receptor B
Molecular Weight	The recombinant rhesus IL17RB consists of 512 amino acids and predicts a molecular mass of 57 kDa.
predicted N	Arg 18
SDS-PAGE
Purity	> 85 % as determined by SDS-PAGE.
Protein Construction	A DNA sequence encoding the rhesus IL17RB (EHH16291.1) (Met1-Gly288) was expressed with the Fc region of human IgG1 at the C-terminus.
Bio-activity
Research Area	Epigenetics \|Cell cycle \|Cell Differentiation
Formulation	Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Rickel EA, et al.. (2008) Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 181(6): 4299-310. Stock P, et al.. (2009) Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J Immunol. 182(8): 5116-22. Wang H, et al.. (2010) Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy. 40(8): 1194-202.