Mouse STHM / ST6GALNAC2 Protein (His Tag)

II,Siat7,Siat7b,ST6GalNAc

Catalog Number	P50774-M08H
Organism Species	Mouse
Host	Human Cells
Synonyms	II,Siat7,Siat7b,ST6GalNAc
Molecular Weight	The secreted recombinant mouse ST6GALNAC2 comprises 357 amino acids and has a calculated molecular mass of 40.7 kDa. The apparent molecular mass of rmST6GALNAC2 is approximately 44 kDa in SDS-PAGE under reducing conditions.
predicted N	Ser 28
SDS-PAGE
Purity	> 98 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the extracellular domain of mouse ST6GALNAC2 (P70277) (Ser 28-Arg 373) was expressed, with a C-terminal polyhistidine tag.
Bio-activity
Research Area
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Li GS, et al. (2007) Variants of the ST6GALNAC2 promoter influence transcriptional activity and contribute to genetic susceptibility to IgA nephropathy. Hum Mutat. 28(10): 950-7. Ding JX, et al. (2009) Activity of alpha2,6-sialyltransferase and its gene expression in peripheral B lymphocytes in patients with IgA nephropathy. Scand J Immunol. 69(2): 174-80. Kiryluk K, et al. (2010) Genetic studies of IgA nephropathy: past, present, and future. Pediatr Nephrol. 25(11): 2257-68.