Mouse PIGF / PLGF Protein (Fc Tag)

AI854365,PIGF,Plgf

Catalog Number	P50125-M02H
Organism Species	Mouse
Host	Human Cells
Synonyms	AI854365,PIGF,Plgf
Molecular Weight	The recombinant mouse PGF/Fc is a disulfide-linked homodimer. The reduced monomer comprises 381 amino acids and has a calculated molecular mass of 42.9 kDa. As a result of glycosylation, the apparent molecular mass of the monomer is approximately 52 kDa in SDS-PAGE under reducing conditions.
predicted N	Val 19
SDS-PAGE
Purity	> 76 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the mouse PGF (P49764) (Met 1-Pro 158) was fused with the Fc region of human IgG1 at the C-terminus.
Bio-activity
Research Area	Signaling \|Signal Transduction \|Growth Factor & Receptor \|Vascular Endothelial Growth Factor (VEGF) & Receptor \|Vascular Endothelial Growth Factor (VEGF)
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Nagy JA, et al. (2003) VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med. 13(5): 169-75. Chaballe L, et al. (2011) Placental growth factor: a tissue modelling factor with therapeutic potentials in neurology? Acta Neurol Belg. 111(1): 10-7. Odorisio T, et al. (2006) The placenta growth factor in skin angiogenesis. J Dermatol Sci. 41(1): 11-9.