Mouse KLRB1F / NKR-P1F Protein (Fc Tag)

A630024B12Rik,MGC130065,MGC130066,Nkr-p1f,Nkrp1-f,Nkrp1f

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Catalog Number	P50815-M01H
Organism Species	Mouse
Host	Human Cells
Synonyms	A630024B12Rik,MGC130065,MGC130066,Nkr-p1f,Nkrp1-f,Nkrp1f
Molecular Weight	The recombinant mouse KLRB1F/Fc is a disulfide-linked homodimer. The reduced monomer comprises 411 amino acids and has a calculated molecular mass of 46 kDa. As a result of glycosylation, the apparent molecular mass of the monomer is approximately 52 kDa in SDS-PAGE under reducing conditions.
predicted N	Glu
SDS-PAGE
Purity	> 88 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the extracellular domain of mouse KLRB1F (Q8VD98) (Gln 67-Val 217) was fused with the Fc region of human IgG1 at the N-terminus.
Bio-activity
Research Area
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Kveberg L, et al. (2011) Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse. Immunogenetics. 63(7): 429-36. Aust JG, et al. (2009) The expression and function of the NKRP1 receptor family in C57BL/6 mice. J Immunol. 183(1): 106-16. Tian W, et al. (2005) C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production. Cell Immunol. 234(1): 39-53. Plougastel B, et al. (2001) Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f. Immunogenetics. 53(7): 592-8.