Human Semaphorin 6A / SEMA6A Protein (His Tag)

HT018,SEMA,SEMA6A1,SEMAQ,VIA

Catalog Number	P11189-H08H
Organism Species	Human
Host	Human Cells
Synonyms	HT018,SEMA,SEMA6A1,SEMAQ,VIA
Molecular Weight	The recombinant human SEMA6A consists of 642 amino acids and predictes a molecular mass of 72.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SEMA6A is approximately 85-95 kDa due to glycosylation.
predicted N	Gly 19
SDS-PAGE
Purity	> 90 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human SEMA6A (NP_065847.1) extracellular domain (Met 1-Thr 649) was expressed, with a polyhistidine tag at the C-terminus.
Bio-activity
Research Area	Neuroscience \|Neurology process \|Growth and Development \|Axon Guidance \|Semaphorin, Plexin, & Neuropilin
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Klostermann A., et al., 2000, J. Biol. Chem. 275:39647-53. Nagase T., et al., 2000, DNA Res. 7:65-73. Schmutz J., et al., 2004, Nature 431:268-74. Neufeld, G. et al., 2005, Front Biosci. 10 : 751-60. Fiore,R. et al., 2005, Mol Cell Biol. 25 (6):2310-9.