Human PDZD11 / PDZK11 / PISP Protein (His Tag)
AIPP1,PDZK11,PISP
- 100ug (NPP2391) Please inquiry
| Catalog Number | P12188-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | AIPP1,PDZK11,PISP |
| Molecular Weight | The recombinant human PDZD11 consisting of 146 amino acids and has a calculated molecular mass of 16.9 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions as predicted. |
| predicted N | Met |
| SDS-PAGE |  |
| Purity | > 97 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human PDZD11 (NP_057568.1) (Asp 2-His 140) was expressed, with a polyhistide tag at the N-terminus. |
| Bio-activity | |
| Research Area | Cancer |Signal transduction |Other Signal Transduction Molecules |
| Formulation | Lyophilized from sterile PBS, pH 8.0 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11. |
| Reference |