Human KYNU / Kynureninase Protein (His Tag)

KYNUU

Catalog Number	P10841-H08B
Organism Species	Human
Host	Baculovirus-Insect Cells
Synonyms	KYNUU
Molecular Weight	The recombinant human KYNU consists of 475 amino acids and predicts a molecular mass of 53.7 kDa. The apparent molecular mass of rhKYNU is approximately 47 kDa in SDS-PAGE under reducing conditions.
predicted N	Met
SDS-PAGE
Purity	> 92 % as determined by SDS-PAGE
Protein Construction	The recombinant human KYNU consists of 475 amino acids and predicts a molecular mass of 53.7 kDa. The apparent molecular mass of rhKYNU is approximately 47 kDa in SDS-PAGE under reducing conditions.
Bio-activity	Measured by its ability to oxidize 3-hydroxykynurenine. The specific activity is > 200 pmoles/min/μg.
Research Area	Neuroscience \|Cell Type Marker in Neurodevelopment \|Neuronal Cell Markers \|Synapse & Synaptic Proteins \|Postsynaptic Density Protein
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 25% gly 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Lima S, et al. (2007) Crystal structure of Homo sapiens kynureninase. Biochemistry. 46(10): 2735-44. Momany C, et al. (2004) Three-dimensional structure of kynureninase from Pseudomonas fluorescens. Biochemistry. 43(5): 1193-203. Toma S, et al. (1997) Cloning and recombinant expression of rat and human kynureninase. FEBS Lett. 408(1): 5-10.