Human COL5A2 Protein (Fc Tag)
COL5A2
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| Catalog Number | P13685-H05H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | COL5A2 |
| Molecular Weight | The recombinant human COL5A2/mFc is a disulfide-linked homodimer. The reduced monomer comprises 1437 amino acids and has a predicted molecular mass of 138.6 kDa. The apparent molecular mass of the protein is approximately 75 and 60 in SDS-PAGE under reducing conditions. |
| predicted N | Gln 27 |
| SDS-PAGE |  |
| Purity | (26.7+59.2) % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human COL5A2(P05997)(Met1-Leu1229) was fused with Fc region of mouse IgG at the C-terminus. |
| Bio-activity | |
| Research Area | Neuroscience |Neurology process |Growth and Development |Axon Guidance |Extracellular Matrix Proteins in Axon Guidance |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange themselves into long, thin fibrils that cross-link to one another in the spaces around cells. The cross-links result in the formation of very strong, mature type V collagen fibers. Type V collagen can be detected in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. |
| Reference |