Human ADCYAP1R1 Protein (Fc Tag)

PAC1,PAC1R,PACAPR,PACAPRI

Catalog Number	P13223-H02H
Organism Species	Human
Host	Human Cells
Synonyms	PAC1,PAC1R,PACAPR,PACAPRI
Molecular Weight	The recombinant human ADCYAP1R1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 373 amino acids and has a predicted molecular mass of 42 kDa. The reduced monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
predicted N	Asp 24
SDS-PAGE
Purity	> 88 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human ADCYAP1R1 (P41586) extracellular domain (Met 1-Ala 155) was fused with the Fc region of human IgG1 at the C-terminus.
Bio-activity
Research Area	Signaling \|Signal Transduction \|Signaling Pathway \|G Protein Signaling \|G Protein-Coupled Receptors (GPCRs) \|Neurotransmitter G Protein-Coupled Receptors \|
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Solano RM. et al., 1996, Endocrinology. 137 (7): 2815-22. Miampamba M. et al., 2002, Regul Pept. 105 (3): 145-54. Brabet P. et al., 1997, Genomics. 38 (1): 100-2.