Human ACBD7 Protein (His Tag)
ACBD7
- 100ug (NPP1859) Please inquiry
| Catalog Number | P14561-H07E |
|---|---|
| Organism Species | Human |
| Host | E. coli |
| Synonyms | ACBD7 |
| Molecular Weight | The recombinant human ACBD7 consists of 103 amino acids and predicts a molecular mass of 11.6 KDa. It migrates as an approximately 10 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | His |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the mature form of human ACBD7 (Q8N6N7) (Met1-Ile88) was expressed with a polyhistide tag at the N-terminus. |
| Bio-activity | |
| Research Area | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | ACBD7, acyl-CoA-binding domain-containing protein 7, is a small (10 Kd) protein that contains 1 ACB (acyl-CoA-binding) domain. The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed acyl-CoA-binding site. The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrophobic surfaces of CoA and the protein. Other proteins containing an ACB domain include: ACBP (acyl-CoA-binding protein), ACBD3, ACBD4, ACBD5, ACBD6. |
| Reference |