Cynomolgus FCGRT & B2M Heterodimer Protein

FCGRT FCRN & B2M

Catalog Number	PCT031-C08H
Organism Species	Cynomolgus
Host	Human Cells
Synonyms	FCGRT FCRN & B2M
Molecular Weight	The recombinant heterodimer of cyno FCGRT&B2M comprises 384 (285+99) amino acids and has a calculated molecular mass of 43.5 (31.9+ 11.6) KDa. The apparent molecular mass of cyno FCGRT&B2M heterodimer is approximately 35 & 12 KDa respectively in SDS-PAGE
predicted N	Ala 24 & Ile 21
SDS-PAGE
Purity	> 98 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Ser 297) of cyno FCGRT (Q8SPV9) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the cyno B2M (Q6V7J5) (Met 1-Met 119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT/B2M heterodimer was purified.
Bio-activity	Measured by its ability to bind human IgG1 in functional ELISA.
Research Area	Immunology \|Innate Immunity \|Fc Receptor
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference